case series of rhinocerebral mucormycosis occurring in diabetic patients

Authors

rasoul mohammadi department of medical parasitology and mycology, faculty of medicine, isfahan university of medical sciences, isfahan, iran

mohsen meidani department of infectious diseases, al-zahra hospital, isfahan university of medical sciences, isfahan, iran

kamyar mostafavizadeh department of infectious diseases, al-zahra hospital, isfahan university of medical sciences, isfahan, iran

bijan iraj department of endocrinology, isfahan university of medical sciences, isfahan, iran

abstract

background: rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. in most cases, infection is caused by inhalation of fungal spores. mortality rate of patients is very high (40-85%).  case presentation: in this study, three diabetic patients with rhinocerebral mucormycosis were presented. the etiologic agents of mucormycosis in two patients were isolated and identified by sequence analysis and data were registered in gene bank database.  conclusion: in patients with mucormeosis, early detection, surgical excision and appropriate debridement, suitable antifungal therapy, and control of risk factors like diabetes mellitus are the main parameters of successful management of this lethal infection.

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Journal title:
caspian journal of internal medicine

جلد ۶، شماره ۴، صفحات ۲۴۳-۲۴۶

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